Power And Sample Size Calculator Mac App Download
Command: | Sample size Survival analysis (logrank test) |
Description
Calculates the required sample size for the comparison of survival rates in two independent groups.
- G power for sample size free download - Sample Size, G Power, Sample Size Calculator App, and many more programs.
- So you compute power retrospectively to see if the test was powerful enough or not. This is an empty question. Of course it wasn't powerful enough - that's why the result isn't significant. Power calculations are useful for design, not analysis. (Note: These comments refer to power computed based on the observed effect size and sample size.
(Note: These comments refer to power computed based on the observed effect size and sample size. Considering a different sample size is obviously prospective in nature. Considering a different effect size might make sense, but probably what you really need to do instead is.
Required input
- Type I error - alpha: the probability of making a Type I error (α-level, two-sided), i.e. the probability of rejecting the null hypothesis when in fact it is true.
- Type II error - beta: the probability of making a Type II error (β-level), i.e. the probability of accepting the null hypothesis when in fact it is false.
- Survival rate Group 1: the hypothesized survival rate in the first group.
- Survival rate Group 2: the hypothesized survival rate in the second group.
- Ratio of sample sizes in Group 1 / Group 2: the ratio of the sample sizes in group 1 and 2. Enter 1 for equal sample sizes in both groups. Enter 2 if the number of cases in group 1 must be double of the number of cases in group 2.
Example
You are interested in detecting a difference between survival rates of 0.6 and 0.4. You plan to have twice as many cases in the first group as in the second group.
For α-level you select 0.05 and for β-level you select 0.20 (power is 80%).
Enter the values 0.6 and 0.4 for the Survival rates in Group 1 and Group 2, and enter 2 for the Ratio of sample sizes.
Results
After you click Calculate the program displays the required sample size.
In the example 129 cases are required in Group 1 and 65 cases in Group 2, giving a total of 194 cases.
A table shows the required total sample size for different Type I and Type II Error levels.
Literature
- Machin D, Campbell MJ, Tan SB, Tan SH (2009) Sample size tables for clinical studies. 3rd ed. Chichester: Wiley-Blackwell.
See also
Recommended book
Sample Size Tables for Clinical Studies
David Machin, Michael J. Campbell, Say-Beng Tan, Sze-Huey Tan
Buy from Amazon US - CA - UK - DE - FR - ES - IT
Sample Sizes for Clinical, Laboratory and Epidemiology Studies includes the sample size software (SSS) and formulae and numerical tables needed to design valid clinical studies. The text covers clinical as well as laboratory and epidemiology studies and contains the information needed to ensure a study will form a valid contribution to medical research.
Free Calculator For Mac
The authors, noted experts in the field, explain step by step and explore the wide range of considerations necessary to assist investigational teams when deriving an appropriate sample size for their when planned study. The book contains sets of sample size tables with companion explanations and clear worked out examples based on real data. In addition, the text offers bibliography and references sections that are designed to be helpful with guidance on the principles discussed. S1 stereo imager vst download.